risk of depression from insulin resistance; There is also complaint of constant sadness, hopelessness, lethargy and loss of appetite.
Insulin plays an important role in diabetes. In this disease, many vital organs gradually become weak or deteriorate. Now a new research has shown that the body's resistance to insulin doubles the risk of developing severe depression. The findings have been published in the American Journal of Psychiatry.
Insulin resistance occurs when muscle, fat (fat) and liver (liver) cells do not respond appropriately to insulin and cannot use glucose from the blood for energy.
Ratali Rasgon, a professor of psychiatry and behavioral sciences at the University of Amsterdam Medical Center, said that if you have insulin resistance, you are twice as likely to be depressed than the general population, even if you have not had such a complaint before. Symptoms include persistent sadness, hopelessness, lethargy, sleep disturbances, and loss of appetite. However, factors such as an accident in childhood, the death of a loved one can also contribute to these disorders, which cannot be prevented. But insulin resistance is preventable and can be achieved through diet, exercise, and medications. Numerous studies confirm that usually one in three people suffer from insulin resistance and they are not even aware of it.
This condition is not caused by a reduced ability of the pancreas to secrete insulin into the bloodstream, as occurs in type 1 diabetes. Rather, this condition occurs due to the alertness of controlling this hormone in the cells of the whole body. Actually, the job of insulin is to tell the cells to process the glucose present in the blood (which is produced by food and liver).
Every cell uses glucose as fuel, and every cell has receptors on its surface that bind to insulin and signal it to take up an energy source.
Why and how is the problem
The reality is that the number of people with insulin resistance is increasing worldwide. The main reasons for this are consuming more calories, lack of exercise, stress and not getting enough sleep due to various reasons. Because of this, the insulin receptor is unable to bind to insulin properly. Even if blood sugar remains high.
Once the sugar level rises above a certain threshold, type 2 diabetes occurs, which is curable. But if proper treatment is not done, apart from heart and kidney related diseases, there may also be a chance of amputation of organs. Overall, there is a big side effect on health.
Insulin resistance has been proven to be associated with a variety of mental disorders. For example, it has also been found that 40 percent of people with mood disorders have insulin resistance. But the question remains unanswered for the time being whether it is caused by just one event or whether there are any factors in it. A longer study was needed to find out.
how did you study
Researchers obtained data from three thousand people included in The Netherlands Study of Depression and Anxiety. This study focused on the causes and effects of depression. They had no complaints of depression or anxiety when they were registered for the study. The mean age of the participants was 41 years.
The researchers measured three indicators of insulin resistance—abdominal glucose levels, waist measurement, and high-density lipoprotein (HDL) or good cholesterol in the blood. Then for nine years, they looked at the risk of developing depression.
found that a slight increase in insulin resistance, measured by the ratio of triglyceride to HDL, was associated with an 89 percent increase in the rate of new cases of depressive disorder.
Similarly, for every five centimeter increase in abdominal fat, the risk of depression was 11 percent higher. Whereas with an increase of 18 mg per deciliter of blood in fasting plasma glucose, the risk of developing depression was found to be 37 percent higher.